Pulse Pressure in Clinical Practice CARDIOVASCULAR RISK FACTORS | ORIGINAL RESEARCH
نویسندگان
چکیده
Pulse pressure (PP) is defined as the difference between systolic blood pressure (SBP) and diastolic blood pressure (DBP). Physiologically, both pressures increase throughout life due to the increase of stroke volume and/or peripheral vascular resistance (PVR). In the sixth decade of age, the PP increases with increasing SBP and decreasing DBP due to an increase of arterial stiffness [1]. The PP increase also leads to higher pulse wave velocity (PWV). Both PP and PWV are important independent prognostic markers of cardiovascular morbidity and mortality [2]. The older people are, the more they are at risk of cardiovascular events, and the high prevalence of isolated systolic hypertension accompanied by a wide pulse pressure seems to be one of the most important factors [3].
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